Introduced in 2016 and published in 2017 in Nature Methods, eC-CLEM is the reference for image registration in multimodal imaging approaches.
Free and open-source, it is likely your fastest solution to have quantitative image registration with registration error metrics
To go beyond the first sight and automate your workflows, Autofinder will be your next step. More informations here
We also give regular training on it, stay tuned or contact us for more infos.