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Freeze Substitution
Once a sample has been vitrified by High Pressure Freezing, it is convenient to warm it back to room temperature for further analysis by electron microscopy. To prevent damages to the specimen during...
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High Pressure Freezing
High Pressure Freezing is a technology that aim to vitrify hydrated specimen up to 200µm in thickness. To achieve that, we exploit in part the water phase diagram and circumvent the ice transition...